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Poster De Conférence Année : 2023

The Level of Methionine Deficiency Determines Its Effects on Energy Metabolism in Growing Rats

Résumé

The level of methionine deficiency determines its effects on energy metabolism in growing rats. Funding sources: Methionine deficiency has been reported as beneficial for health through an increase in energy expenditure and an improvement of insulin sensitivity, which in turn lowers blood lipids and adiposity, despite an increased energy intake. Thus, the aim of this study is to characterize the effects of different methionine deficient levels on growth, body composition, and energy metabolism in growing rats. However, when fed to young animals, methionine-deficient diets are not suitable for growth. In the majority of studies, the consequences of methionine deficiency have been studied on the same level (0.17% of diet). This study shows that the level of methionine deficiency is crucial to understand its effects in young rats. For a severe deficiency, food intake can not offset methionine deficiency and growth retardation, whereas for a moderate level of methionine deficiency, the food intake increased and energy expenditure can not offset the excess of energy intake, leading to a higher fat mass.
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Dates et versions

hal-04312787 , version 1 (28-11-2023)

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Gaëtan Roisné-Hamelin, Catherine C. Chaumontet, Anne Blais, Julien Piedcoq, Claire Gaudichon, et al.. The Level of Methionine Deficiency Determines Its Effects on Energy Metabolism in Growing Rats. The American Society for Nutrition’s, Jul 2023, Boston (USA), United States. Elvesier, Current Developments in Nutrition, 7 (Supplement 1), pp.304, 2023, ⟨10.1016/j.cdnut.2023.100794⟩. ⟨hal-04312787⟩
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