The Level of Methionine Deficiency Determines Its Effects on Energy Metabolism in Growing Rats
Résumé
The level of methionine deficiency determines its effects on energy metabolism in growing rats. Funding sources: Methionine deficiency has been reported as beneficial for health through an increase in energy expenditure and an improvement of insulin sensitivity, which in turn lowers blood lipids and adiposity, despite an increased energy intake. Thus, the aim of this study is to characterize the effects of different methionine deficient levels on growth, body composition, and energy metabolism in growing rats. However, when fed to young animals, methionine-deficient diets are not suitable for growth. In the majority of studies, the consequences of methionine deficiency have been studied on the same level (0.17% of diet). This study shows that the level of methionine deficiency is crucial to understand its effects in young rats. For a severe deficiency, food intake can not offset methionine deficiency and growth retardation, whereas for a moderate level of methionine deficiency, the food intake increased and energy expenditure can not offset the excess of energy intake, leading to a higher fat mass.
Domaines
Alimentation et NutritionOrigine | Fichiers produits par l'(les) auteur(s) |
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