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4-Oxo-1,4-dihydropyridines as Selective CB 2 Cannabinoid Receptor Ligands Part 2: Discovery of New Agonists Endowed with Protective Effect Against Experimental Colitis

Jamal El Bakali , Pauline Gilleron , Mathilde Body-Malapel , Roxane Mansouri , Giulio G. Muccioli , et al.
Journal of Medicinal Chemistry, 2012, 55 (20), pp.8948 - 8952. ⟨10.1021/jm3008568⟩
Journal articles hal-01935815v1
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Protein chemical synthesis in medicinal chemistry

Vangelis Agouridas , Ouafâa El Mahdi , Oleg Melnyk
Journal of Medicinal Chemistry, 2020, 63 (24), pp.15140-15152. ⟨10.1021/acs.jmedchem.0c01082⟩
Journal articles hal-03053521v1
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The Problem of Aspartimide Formation During Protein Chemical Synthesis Using SEA-Mediated Ligation

Jennifer Bouchenna , Magalie Sénéchal , Hervé Drobecq , Jérôme Vicogne , Oleg Melnyk
Peptide and Protein Engineering, pp.13-28, 2020, 978-1-0716-0720-6. ⟨10.1007/978-1-0716-0720-6_2⟩
Book sections hal-02995426v1

Anchorage of Synthetic Peptides onto Liposomes via Hydrazone and α-Oxo Hydrazone Bonds. Preliminary Functional Investigations

Line Bourel-Bonnet , Eve-Isabelle Pécheur , Cyrille Grandjean , Annick Blanpain , Thorsten Baust , et al.
Bioconjugate Chemistry, 2005, 16 (2), pp.450-457. ⟨10.1021/bc049908v⟩
Journal articles istex hal-02196954v1
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The Role of the Conserved SUMO-2/3 Cysteine Residue on Domain Structure Investigated Using Protein Chemical Synthesis

Jennifer Bouchenna , Magalie Sénéchal , Hervé Drobecq , Nicolas Stankovic-Valentin , Jérôme Vicogne , et al.
Bioconjugate Chemistry, 2019, 30 (10), pp.2684-2696. ⟨10.1021/acs.bioconjchem.9b00598⟩
Journal articles hal-02349318v1
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Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients.

Harry Sokol , Bénédicte Pigneur , Laurie Watterlot , Omar Lakhdari , Luis G Bermúdez-Humarán , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2008, 105 (43), pp.16731-6. ⟨10.1073/pnas.0804812105⟩
Journal articles hal-00652961v1

First characterization of SmOPG1, a novel protein involved in gonad-associated processes in Schistosoma mansoni

Steffen Hahnel , Richard Parker-Manuel , Colette Dissous , Katia Cailliau-Maggio , Christoph G. Grevelding
Molecular and Biochemical Parasitology, 2017, Molecular and Biochemical Parasitology, 213, pp.22-25. ⟨10.1016/j.molbiopara.2017.01.007⟩
Journal articles hal-03174835v1
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Synthesis and pharmacological evaluation of benzamide derivatives as potent and selective sigma-1 protein ligands

Marion Donnier-Marechal , Pascal Carato , Paul-Emmanuel Larchanché , Séverine Ravez , Rajâa Boulahjar , et al.
European Journal of Medicinal Chemistry, 2017, 138, pp.964-978. ⟨10.1016/j.ejmech.2017.07.014⟩
Journal articles hal-02011792v1

Design, synthesis and evaluation of 2-aryl benzoxazoles as promising hit for the A2A receptor

Romain Duroux , Nicolas Renault , Joana Esteves , Laurence Agouridas , David Blum , et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2017, 32 (1), pp.850-864. ⟨10.1080/14756366.2017.1334648⟩
Journal articles hal-02060508v1
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New phenylaniline derivatives as modulators of amyloid protein precursor metabolism

Marion Gay , Pascal Carato , Mathilde Coevoet , Nicolas Renault , Paul-Emmanuel Larchanché , et al.
Bioorganic and Medicinal Chemistry, 2018, 26 (8), pp.2151-2164. ⟨10.1016/j.bmc.2018.03.016⟩
Journal articles hal-02060708v1

Access to 3-spiroindolizines containing an isoindole ring through intra-molecular arylation of spiro-N-acyliminium species: a new family of potent farnesyltransferase inhibitors

Anthony Pesquet , Hamid Marzag , Michael Knorr , Carsten Strohmann , Ata Martin Lawson , et al.
Organic & Biomolecular Chemistry, 2019, 17 (10), pp.2798-2808. ⟨10.1039/c8ob02612b⟩
Journal articles hal-02332627v1

Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease

Germain Homerin , Samir Jawhara , Xavier Dezitter , Davy Baudelet , Pierrick Dufrénoy , et al.
Journal of Medicinal Chemistry, 2019, Women in Medicinal Chemistry, Epub ahead of print, ⟨10.1021/acs.jmedchem.9b00584⟩
Journal articles hal-02376260v1

Access to newly functionalized imidazole derivatives: efficient synthesis of novel 5-amino-2-thioimidazoles using propylphosphonic anhydride (®T3P)

Manuel Lasalle , Sylvain Picon , Rajâa Boulahjar , Vanessa Hoguet , Jolien van Obbergen , et al.
Tetrahedron Letters, 2015, 56 (8), pp.1011-1014. ⟨10.1016/j.tetlet.2015.01.046⟩
Journal articles hal-02268874v1

Layer-by-layer coating of textile with two oppositely charged cyclodextrin polyelectrolytes for extended drug delivery

Jatupol Junthip , Nicolas Tabary , Feng Chai , Laurent Leclercq , Mickael Maton , et al.
Journal of Biomedical Materials Research Part A, 2016, 104 (6), pp.1408-1424. ⟨10.1002/jbm.a.35674⟩
Journal articles istex hal-02322748v1

Probing the role of the covalent linkage of ferrocene into a chloroquine template

Christophe Biot , Wassim Daher , Cheikh M. Ndiaye , Patricia Melnyk , Bruno Pradines , et al.
Journal of Medicinal Chemistry, 2006, 49, pp.4707-4714. ⟨10.1021/jm060259d⟩
Journal articles istex hal-00097346v1

Hydroxylamine-functionalised silica surfaces for biochip applications

Martin Franck , Diran Anne , Jean-Olivier Durand , Granier Michel , Desmet Rémi
Tetrahedron Letters, 2005, pp.7973-7975. ⟨10.1016/j.tetlet.2005.09.084⟩
Journal articles istex hal-00381716v1
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UDP-GLYCOSYLTRANSFERASE 72E3 Plays a Role in Lignification of Secondary Cell Walls in Arabidopsis

Fabien Baldacci-Cresp , Julien Le Roy , Brigitte Huss , Cedric Lion , Anne Creach , et al.
International Journal of Molecular Sciences, 2020, International journal of molecular sciences, 21 (17), pp.6094. ⟨10.3390/ijms21176094⟩
Journal articles hal-03030963v1

A One-Pot Three-Segment Ligation Strategy for Protein Chemical Synthesis

Nathalie Ollivier , Jérôme Vicogne , Aurélie Vallin , Hervé Drobecq , Rémi Desmet , et al.
Angewandte Chemie International Edition, 2011, 51 (1), pp.209-213. ⟨10.1002/anie.201105837⟩
Journal articles istex hal-03104069v1
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Comment on “N-terminal Protein Tail Acts as Aggregation Protective Entropic Bristles: The SUMO Case”

Magalie Sénéchal , Jennifer Bouchenna , Jérôme Vicogne , Oleg Melnyk
Biomacromolecules, 2020, 21 (8), pp.3480-3482. ⟨10.1021/acs.biomac.0c00185⟩
Journal articles hal-02995257v1
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SEA-Mediated Ligation Is Accelerated at Mildly Acidic pH: Application to the Formation of Difficult Peptide Junctions

Marine Cargoët , Vincent Diemer , Laurent Raibaut , Elizabeth Lissy , Benoît Snella , et al.
Peptide and Protein Engineering, pp.1-12, 2020, 978-1-0716-0720-6. ⟨10.1007/978-1-0716-0720-6_1⟩
Book sections hal-02995395v1

CoO Promoted the Catalytic Activity of Nitrogen-Doped MoS 2 Supported on Carbon Fibers for Overall Water Splitting

Liuqing Pang , Alexandre Barras , Yuan Zhang , Mohammed Amin , Ahmed Addad , et al.
ACS Applied Materials & Interfaces, 2019, 11 (35), pp.31889-31898. ⟨10.1021/acsami.9b09112⟩
Journal articles hal-02368050v1

Improved synthesis, resolution, absolute configuration determination of HLM006474 enantiomer

Patrick Meffre , Miyanou Rosales-Hurtado , Alexandre Lebeau , Gerardo Cebrian Cebrian-Torrejon , Muriel Albalat , et al.
XXII International conférence on Organic synthesis (22-ICOS), Sep 2018, Florence, Italy
Conference poster hal-02011288v1

Spleen-Resident CD4+ and CD4− CD8α− Dendritic Cell Subsets Differ in Their Ability to Prime Invariant Natural Killer T Lymphocytes

Emilie Bialecki , Elodie Macho Fernandez , Stoyan Ivanov , Christophe Paget , Josette Fontaine , et al.
PLoS ONE, 2011, 6 (10), pp.e26919. ⟨10.1371/journal.pone.0026919⟩
Journal articles hal-02361403v1
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Des protéines de synthèse taillées sur mesure pour investiguer le vivant

Vincent Aucagne , Fabienne Burlina , Oleg Melnyk , Vladimir Torbeev
L'Actualité Chimique, 2021, 468, pp.26-28
Journal articles hal-02959387v1

Combining Click Reactions for the One-Pot Synthesis of Modular Biomolecule Mimetics

Anne Brinkø , Christian Risinger , Annie Lambert , Ola Blixt , Cyrille Grandjean , et al.
Organic Letters, 2019, 21 (18), pp.7544-7548. ⟨10.1021/acs.orglett.9b02811⟩
Journal articles hal-02346734v1

Identification of novel quinazoline derivatives as potent antiplasmodial agents

Anne Bouchut , Dante Rotili , Christine Pierrot , Sergio Valente , Sophia Lafitte , et al.
European Journal of Medicinal Chemistry, 2019, 161, pp.277-291. ⟨10.1016/j.ejmech.2018.10.041⟩
Journal articles pasteur-03036828v1

Conformational Restriction Leading to a Selective CB 2 Cannabinoid Receptor Agonist Orally Active Against Colitis

Jamal El Bakali , Giulio G. Muccioli , Mathilde Body-Malapel , Madjid Djouina , Frédérique Klupsch , et al.
ACS Medicinal Chemistry Letters, 2015, 6 (2), pp.198 - 203. ⟨10.1021/ml500439x⟩
Journal articles hal-01935803v1
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Probing Long‐Range Anisotropic Interactions: a General and Sign‐Sensitive Strategy to Measure 1 H– 1 H Residual Dipolar Couplings as a Key Advance for Organic Structure Determination

Davy Sinnaeve , Julian Ilgen , Maria Enrica Di Pietro , Johann Primozic , Volker Schmidts , et al.
Angewandte Chemie International Edition, 2020, 59 (13), pp.5316-5320. ⟨10.1002/anie.201915278⟩
Journal articles hal-02538220v1

Semisynthetic glycoconjugate based on dual role protein/PsaA as a pneumococcal vaccine

Maruthi Prasanna , Daphnée Soulard , Emilie Camberlein , Nicolas Ruffier , Annie Lambert , et al.
European Journal of Pharmaceutical Sciences, 2019, 129, pp.31-41. ⟨10.1016/j.ejps.2018.12.013⟩
Journal articles hal-02197013v1

Reprogramming Escherichia coli for the production of prenylated indole diketopiperazine alkaloids

Pavlina Dubois , Isabelle Correia , Fabien Le Chevalier , Steven Dubois , Isabelle Jacques , et al.
Scientific Reports, 2019, 9 (1), pp.9208. ⟨10.1038/s41598-019-45519-y⟩
Journal articles hal-03982770v1