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Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis

F. Le Cann , C. Delehouzé , S. Leverrier-Penna , A. Filliol , A. Comte , et al.
FEBS Journal, 2017, 284 (18), pp.3050-3068. ⟨10.1111/febs.14176⟩
Journal articles hal-01616420v1

Microwave synthesis of new 3-(3-aminopropyl)-5-arylidene-2-thioxo-1,3-thiazolidine-4-ones as potential Ser/Thr protein kinase inhibitors

Camille Déliko Dago , Wacothon Karime Coulibaly , Yves-Alain Bekro , Janat A. Mamyrbekova-Bekro , Beatrice Foll-Josselin , et al.
Medicinal Chemistry Research, 2016, 25 (12), pp.2940--2958. ⟨10.1007/s00044-016-1719-3⟩
Journal articles hal-01414293v1

Synthesis of N-pyridyl azoles using a deprotometalation-iodolysis-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells

Madani Hedidi , Julien Maillard , William Erb , Frédéric Lassagne , Yury Halauko , et al.
Tetrahedron, 2016, 72 (39), pp.6467 - 6476. ⟨10.1016/j.tet.2016.08.056⟩
Journal articles hal-03875302v1

Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1

Espérance Moine , Isabelle Dimier-Poisson , Cécile Enguehard-Gueiffier , Cédric Logé , Mélanie Pénichon , et al.
European Journal of Medicinal Chemistry, 2015, 105, pp.80-105. ⟨10.1016/j.ejmech.2015.10.004⟩
Journal articles hal-02389861v1

Further investigation of Paprotrain: Towards the conception of selective and multi-targeted CNS kinase inhibitors

Christophe Labrière , Olivier Lozach , Mélina Blairvacq , Laurent Meijer , Catherine Guillou
European Journal of Medicinal Chemistry, 2016, 124, pp.920 - 934. ⟨10.1016/j.ejmech.2016.08.069⟩
Journal articles hal-01517780v1

Développement de nouveaux inhibiteurs de TgCDPK1 à visée anti-toxoplasmique

Espérance Moine , Isabelle Dimier-Poisson , Cécile Enguehard-Gueiffier , Cedric Logé , Mélanie Pénichon , et al.
6. Journées du Consortium antiParasitaire et antiFongique : CaPF-2016 " A la croisée des Mondes !", Consortium Anti-Parasitaire et Fongique (CaPF). FRA., Mar 2016, Tours, France. 49 p
Conference papers hal-02739722v1

From Peptide Aptamers to Inhibitors of FUR, Bacterial Transcriptional Regulator of Iron Homeostasis and Virulence

Sophie Mathieu , Cheickna Cissé , Sylvie Vitale , Aynur Ahmadova , Mélissa Degardin , et al.
ACS Chemical Biology, 2016, 11 (9), pp.2519-2528. ⟨10.1021/acschembio.6b00360⟩
Journal articles hal-01354302v1

Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors

Aziz Ouach , Rajâa Boulahjar , Christine Vala , Stéphane Bourg , Pascal Bonnet , et al.
European Journal of Medicinal Chemistry, 2016, 115, pp.311--325. ⟨10.1016/j.ejmech.2016.02.072⟩
Journal articles hal-01295635v1

Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines

Pascal Marchand , Marc-Antoine Bazin , Fabrice Pagniez , Guillaume Rivière , Lizeth Bodero , et al.
European Journal of Medicinal Chemistry, 2015, 103, pp.381-395. ⟨10.1016/j.ejmech.2015.09.002⟩
Journal articles hal-03216056v1

New insight in ARX-mutated patients' language specific impairment and underlying FOXP1 dysregulation

A. Curie , G. Friocourt , S. Bertrand , F. Rochefort , N. Loaëc , et al.
European Journal of Paediatric Neurology, 2017, 21, pp.e66. ⟨10.1016/j.ejpn.2017.04.936⟩
Journal articles hal-02871228v1

Synthesis and molecular modelling studies of 8-arylpyrido[3',2':4,5thieno[3,2-d]pyrimidin-4-amines as multitarget Ser/Thr kinases inhibitors

Yvonnick Loidreau , Emmanuel Deau , Pascal Marchand , Marie-Renée Nourrisson , Cédric Logé , et al.
European Journal of Medicinal Chemistry, 2015, 92, pp.124-134. ⟨10.1016/j.ejmech.2014.12.038⟩
Journal articles hal-01135195v1

The pathogenic m.8993 T > G mutation in mitochondrial ATP6 gene prevents proton release from the subunit c -ring rotor of ATP synthase

Xin Su , Alain Dautant , Malgorzata Rak , François Godard , Nahia Ezkurdia , et al.
Human Molecular Genetics, 2021, 30 (5), pp.381-392. ⟨10.1093/hmg/ddab043⟩
Journal articles hal-03830051v1

Deregulating mitochondrial metabolite and ion transport has beneficial effects in yeast and human cellular models for NARP syndrome

Xin Su , Malgorzata Rak , Emmanuel Tetaud , François Godard , Elodie Sardin , et al.
Human Molecular Genetics, 2019, 28 (22), pp.3792-3804. ⟨10.1093/hmg/ddz160⟩
Journal articles hal-02362008v1

Tampering with Cell Division by Using Small-Molecule Inhibitors of CDK-CKS Protein Interactions

Amel Hamdi , Aurélien Lesnard , Peggy Suzanne , Thomas Robert , Maria A. Miteva , et al.
ChemBioChem, 2015, 16 (3), pp.432-439. ⟨10.1002/cbic.201402579⟩
Journal articles istex hal-02043908v1