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cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease.

Xavier Fant , Emilie Durieu , Gaëtan Chicanne , Bernard Payrastre , Diego Sbrissa , et al.
Molecular Pharmacology, 2014, 85 (3), pp.441-50. ⟨10.1124/mol.113.090837⟩
Journal articles inserm-01012086v1

Synthesis and biological evaluation of tetrahydro[1,4]diazepino[1,2-a]indol-1-ones as cyclin-dependent kinase inhibitors

Putey Aurelien , Fournet Guy , Olivier Lozach , Lionel Perrin , Meijer Laurent , et al.
European Journal of Medicinal Chemistry, 2014, 83, pp.617-629
Journal articles hal-01147615v1

Acridone Alkaloids from Glycosmis chlorosperma as DYRK1A Inhibitors

Mehdi A. Beniddir , Erell Le Borgne , Bogdan I. Iorga , Nadège Loaëc , Olivier Lozach , et al.
Journal of Natural Products, 2014, 77 (5), pp.1117-1122. ⟨10.1021/np400856h⟩
Journal articles hal-01162685v1

Impact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis.

Marie Jarry , Céline Lecointre , Céline Malleval , Laurence Desrues , Marie-Thérèse Schouft , et al.
Neuro-Oncology, 2014, 16 (11), pp.1484-98
Journal articles hal-01109355v1

Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1

Espérance Moine , Isabelle Dimier-Poisson , Cécile Enguehard-Gueiffier , Cédric Logé , Mélanie Pénichon , et al.
European Journal of Medicinal Chemistry, 2015, 105, pp.80-105. ⟨10.1016/j.ejmech.2015.10.004⟩
Journal articles hal-02389861v1

Synthesis and evaluation of the antiproliferative activity of novel thiazoloquinazolinone kinases inhibitors.

Alexandra Testard , Laurent Picot , Olivier Lozach , Melina Blairvacq , Laurent Meijer , et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2005, 20 (6), pp.557-568. ⟨10.1080/14756360500212399⟩
Journal articles hal-01443570v1

Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines

Pascal Marchand , Marc-Antoine Bazin , Fabrice Pagniez , Guillaume Rivière , Lizeth Bodero , et al.
European Journal of Medicinal Chemistry, 2015, 103, pp.381-395. ⟨10.1016/j.ejmech.2015.09.002⟩
Journal articles hal-03216056v1

Novel Tetrahydropyrido[1,2-a]isoindolone Derivatives (Valmerins): Potent Cyclin-Dependent Kinase/Glycogen Synthase Kinase 3 Inhibitors with Antiproliferative Activities and Antitumor Effects in Human Tumor Xenografts

Rajâa Boulahjar , Aziz Ouach , Chiurato Matteo , Stéphane Bourg , Myriam Ravache , et al.
Journal of Medicinal Chemistry, 2012, 55, pp.9589-9606
Journal articles hal-00785213v1

Synthesis and molecular modelling studies of 8-arylpyrido[3',2':4,5thieno[3,2-d]pyrimidin-4-amines as multitarget Ser/Thr kinases inhibitors

Yvonnick Loidreau , Emmanuel Deau , Pascal Marchand , Marie-Renée Nourrisson , Cédric Logé , et al.
European Journal of Medicinal Chemistry, 2015, 92, pp.124-134. ⟨10.1016/j.ejmech.2014.12.038⟩
Journal articles hal-01135195v1

Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection

Najma Rachidi , Jean François Taly , Emilie Durieu , Olivier Leclercq , Nathalie Aulner , et al.
Antimicrobial Agents and Chemotherapy, 2014, 58 (3), pp.1501-1515. ⟨10.1128/AAC.02022-13⟩
Journal articles pasteur-01433412v1

3,6-Diamino-4-(2-halophenyl)-2-benzoylthieno[2,3-b]pyridine-5-carbonitriles are Selective Inhibitors of Plasmodium falciparum Glycogen Synthase Kinase-3 (PfGSK-3)

Wiebke Fugel , Anselm Erich Oberholzer , Bernhard Gschloessl , Ron Dzikowski , Narkiss Pressburger , et al.
Journal of Medicinal Chemistry, 2013, 56 (1), pp.264-275. ⟨10.1021/jm301575n⟩
Journal articles hal-02646531v1

Tampering with Cell Division by Using Small-Molecule Inhibitors of CDK-CKS Protein Interactions

Amel Hamdi , Aurélien Lesnard , Peggy Suzanne , Thomas Robert , Maria A. Miteva , et al.
ChemBioChem, 2015, 16 (3), pp.432-439. ⟨10.1002/cbic.201402579⟩
Journal articles istex hal-02043908v1