Search - Phosphorylation de protéines et Pathologies Humaines Access content directly

Filter your results

39 Results
Domains : sdv
Image document

Utilisation de la levure en tant que modèle et outil : de la compréhension de la cytokinèse à l'étude de sélectivité d'une molécule à potentiel thérapeutique

Damien Guiffant
Biologie moléculaire. Rennes 1, 2008. Français. ⟨NNT : ⟩
Theses tel-01112966v1

Impact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis.

Marie Jarry , Céline Lecointre , Céline Malleval , Laurence Desrues , Marie-Thérèse Schouft , et al.
Neuro-Oncology, 2014, 16 (11), pp.1484-98
Journal articles hal-01109355v1
Image document

The Anti-Candida albicans Agent 4-AN Inhibits Multiple Protein Kinases

Maciej Masłyk , Monika Janeczko , Aleksandra Martyna , Sławomir Czernik , Małgorzata Tokarska-Rodak , et al.
Molecules, 2019, 24 (1), pp.153. ⟨10.3390/molecules24010153⟩
Journal articles hal-02046526v1
Image document

The Plasmodium falciparum, Nima-related kinase Pfnek-4: a marker for asexual parasites committed to sexual differentiation.

Luc Reininger , Miguel Garcia , Andrew Tomlins , Sylke Müller , Christian Doerig
Malaria Journal, 2012, 11 (1), pp.250. ⟨10.1186/1475-2875-11-250⟩
Journal articles inserm-00739795v1

Synthesis of N-pyridyl azoles using a deprotometalation-iodolysis-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells

Madani Hedidi , Julien Maillard , William Erb , Frédéric Lassagne , Yury Halauko , et al.
Tetrahedron, 2016, 72 (39), pp.6467 - 6476. ⟨10.1016/j.tet.2016.08.056⟩
Journal articles hal-03875302v1
Image document

High-Throughput Screening of marine resources

Arnaud Hochard , Luc Reininger , Sandrine Ruchaud , Stéphane Bach
Outstanding Marine Molecules, 2015, ⟨10.1002/9783527681501.ch23⟩
Book sections hal-03871307v1
Image document

Redescription and phylogenetic analyses of Durchoniella spp. (Ciliophora, Astomatida) associated with the polychaete Cirriformia tentaculata (Montagu, 1808)

Laure Sauvadet , Denis H. Lynn , Erwan Roussel , Sophie Le Panse , Estelle Bigeard , et al.
European Journal of Protistology, 2017, 61 (Part A), pp.265-277. ⟨10.1016/j.ejop.2017.06.007⟩
Journal articles hal-01578167v1
Image document

Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors

Bruno Oyallon , Marie Brachet-Botineau , Cédric Logé , Pascal Bonnet , Mohamed Souab , et al.
European Journal of Medicinal Chemistry, 2018, 154, pp.101-109. ⟨10.1016/j.ejmech.2018.04.056⟩
Journal articles hal-03408667v1
Image document

Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases

Camille Déliko Dago , Christelle Ambeu , Wacothon-Karime Coulibaly , Yves-Alain Békro , Janat Mamyrbékova , et al.
Molecules, 2015, 20 (7), pp.12412-12435. ⟨10.3390/molecules200712412⟩
Journal articles hal-01187427v1
Image document

Transcriptome and Peptidome Characterisation of the Main Neuropeptides and Peptidic Hormones of a Euphausiid: The Ice Krill, Euphausia crystallorophias

Jean-Yves Toullec , Erwan Corre , Benoit Bernay , Michael A. S. Thorne , Kévin Cascella , et al.
PLoS ONE, 2013, 8 (8), pp.e71609. ⟨10.1371/journal.pone.0071609⟩
Journal articles hal-01250917v1
Image document

Approches moléculaires de la diversité microbienne de deux environnements extrêmes : les sources hydrothermales profondes et les réservoirs pétroliers

Erwan Corre
Biologie moléculaire. Université de Bretagne Occidentale, 2000. Français. ⟨NNT : ⟩
Theses tel-01115381v1
Image document

A Haploid System of Sex Determination in the Brown Alga Ectocarpus sp.

Sophia S. Ahmed , J. Mark Cock , Eugenie Pessia , Remy Luthringer , Alexandre Cormier , et al.
Current Biology - CB, 2014, 24 (17), pp.1945-1957. ⟨10.1016/j.cub.2014.07.042⟩
Journal articles hal-01132642v1

Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis

F. Le Cann , C. Delehouzé , S. Leverrier-Penna , A. Filliol , A. Comte , et al.
FEBS Journal, 2017, 284 (18), pp.3050-3068. ⟨10.1111/febs.14176⟩
Journal articles hal-01616420v1
Image document

Identification de cibles intracellulaires de molécules à activité antiprion

Déborah Tribouillard-Tanvier
Biologie moléculaire. Rennes 1, 2007. Français. ⟨NNT : ⟩
Theses tel-01118256v1

Développement de nouveaux inhibiteurs de TgCDPK1 à visée anti-toxoplasmique

Espérance Moine , Isabelle Dimier-Poisson , Cécile Enguehard-Gueiffier , Cedric Logé , Mélanie Pénichon , et al.
6. Journées du Consortium antiParasitaire et antiFongique : CaPF-2016 " A la croisée des Mondes !", Consortium Anti-Parasitaire et Fongique (CaPF). FRA., Mar 2016, Tours, France. 49 p
Conference papers hal-02739722v1
Image document

A yeast-based assay to isolate drugs active against mammalian prions

Stéphane Bach , Déborah Tribouillard , Nicolas Talarek , Nathalie Desban , Marc Blondel
Methods, 2006, 39 (1), pp.72-77. ⟨10.1016/j.ymeth.2006.04.005⟩
Journal articles hal-02134947v1
Image document

Protein Folding Activity of Ribosomal RNA Is a Selective Target of Two Unrelated Antiprion Drugs

Déborah Tribouillard-Tanvier , Suzana dos Reis , Fabienne Gug , Cécile Voisset , Vincent Béringue , et al.
PLoS ONE, 2008, 3 (5), pp.e2174. ⟨10.1371/journal.pone.0002174⟩
Journal articles hal-02134950v1
Image document

Bioactive Metabolites from the Deep Subseafloor Fungus Oidiodendron griseum UBOCC-A-114129

Marion Navarri , C. Jégou , Arnaud Bondon , Sandrine Pottier , Stéphane Bach , et al.
Marine drugs, 2017, 15 (4), ⟨10.3390/md15040111⟩
Journal articles hal-01518044v1
Image document

Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors.

Rajâa Boulahjar , Aziz Ouach , Stéphane Bourg , Pascal Bonnet , Olivier Lozach , et al.
European Journal of Medicinal Chemistry, 2015, 101, pp.274-287. ⟨10.1016/j.ejmech.2015.06.046⟩
Journal articles hal-01212495v1
Image document

Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors

Amélie Bruel , Romain Bénéteau , Mylène Chabanne , Olivier Lozach , Rémy Le Guevel , et al.
Bioorganic and Medicinal Chemistry Letters, 2014, 24 (21), pp.5037 - 5040. ⟨10.1016/j.bmcl.2014.09.017⟩
Journal articles hal-01086026v1
Image document

Assigning mitochondrial localization of dual localized proteins using a yeast Bi-Genomic Mitochondrial-Split-GFP

Gaétan Bader , Ludovic Enkler , Yuhei Araiso , Marine Hemmerle , Krystyna Binko , et al.
Journal articles hal-02898815v1

Synthesis and evaluation of the antiproliferative activity of novel thiazoloquinazolinone kinases inhibitors.

Alexandra Testard , Laurent Picot , Olivier Lozach , Melina Blairvacq , Laurent Meijer , et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2005, 20 (6), pp.557-568. ⟨10.1080/14756360500212399⟩
Journal articles hal-01443570v1
Image document

Etude de la régulation de deux protéines kinases : GSK-3 et polo

Aline Primot
Biologie cellulaire. Rennes 1, 2001. Français. ⟨NNT : ⟩
Theses tel-01117984v1
Image document

Synthesis of New N,N'-Bis(5-arylidene-4-oxo-4,5-dihydrothiazolin-2-yl)piperazine Derivatives Under Microwave Irradiation and Preliminary Biological Evaluation.

Wacothon Karime Coulibaly , Ludovic Paquin , Anoubilé Bénié , Yves-Alain Bekro , Emilie Durieux , et al.
Scientia Pharmaceutica, 2012, 80 (4), pp.825-36. ⟨10.3797/scipharm.1206-04⟩
Journal articles inserm-00864810v1
Image document

Mécanismes d'action des inhibiteurs de kinases cyclines-dépendantes : identification de leurs cibles intracellulaires par chromatographie d'affinité

Marie Knockaert
Biochimie, Biologie Moléculaire. Université de Bretagne Occidentale, 2002. Français. ⟨NNT : ⟩
Theses tel-01116136v1

Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines

Pascal Marchand , Marc-Antoine Bazin , Fabrice Pagniez , Guillaume Rivière , Lizeth Bodero , et al.
European Journal of Medicinal Chemistry, 2015, 103, pp.381-395. ⟨10.1016/j.ejmech.2015.09.002⟩
Journal articles hal-03216056v1

From Peptide Aptamers to Inhibitors of FUR, Bacterial Transcriptional Regulator of Iron Homeostasis and Virulence

Sophie Mathieu , Cheickna Cissé , Sylvie Vitale , Aynur Ahmadova , Mélissa Degardin , et al.
ACS Chemical Biology, 2016, 11 (9), pp.2519-2528. ⟨10.1021/acschembio.6b00360⟩
Journal articles hal-01354302v1
Image document

Biological Evaluation of Arylsemicarbazone Derivatives as Potential Anticancer Agents

Anne Cecília Nascimento da Cruz , Dalci José Brondani , Temístocles Ítalo de Santana , Lucas Oliveira da Silva , Elizabeth Fernanda da Oliveira Borba , et al.
Pharmaceuticals, 2019, 12 (4), pp.169. ⟨10.3390/ph12040169⟩
Journal articles hal-03864455v1

Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors

Aziz Ouach , Rajâa Boulahjar , Christine Vala , Stéphane Bourg , Pascal Bonnet , et al.
European Journal of Medicinal Chemistry, 2016, 115, pp.311--325. ⟨10.1016/j.ejmech.2016.02.072⟩
Journal articles hal-01295635v1
Image document

Conjugating effects of symbionts and environmental factors on gene expression in deep-sea hydrothermal vent mussels.

Isabelle Boutet , Raymond Ripp , Odile Lecompte , Carole Dossat , Erwan Corre , et al.
BMC Genomics, 2011, 12 (1), pp.530. ⟨10.1186/1471-2164-12-530⟩
Journal articles inserm-00642454v1