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Combination of IM-Based Approaches to Unravel the Coexistence of Two Conformers on a Therapeutic Multispecific mAb

Evolène Deslignière , Simon Ollivier , Anthony Ehkirch , Armelle Martelet , David Ropartz , et al.
Analytical Chemistry, 2022, 94 (22), pp.7981-7989. ⟨10.1021/acs.analchem.2c00928⟩
Journal articles hal-03715025v1

Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors

Ludovic Halby , Nils Marechal , Dany Pechalrieu , Vincent Cura , Don-Marc Franchini , et al.
Philosophical Transactions of the Royal Society B: Biological Sciences, 2018, 373 (1748), pp.20170072. ⟨10.1098/rstb.2017.0072⟩
Journal articles hal-02094589v1
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Cholesterol-pyrene as a probe for cholesterol distribution on ordered and disordered membranes: Determination of spectral wavelengths

Claudia Almeida , Anaë Lle de Wreede , Antonin Lamazière , Jesus Ayala-Sanmartin
Journal articles hal-02335484v1

Aryl hydrocarbon receptor and intestinal immunity

Bruno Lamas , Jane Natividad , Harry Sokol
Mucosal Immunology, 2018, 11 (4), pp. 1024-1038. ⟨10.1038/s41385-018-0019-2⟩
Journal articles hal-03997909v1

Caspase recruitment domain 9, microbiota, and tryptophan metabolism : dangerous liaisons in inflammatory bowel diseases

Bruno Lamas , Mathias Richard , Harry Sokol
Current Opinion in Clinical Nutrition and Metabolic Care, 2017, 20 (4), pp. 243-247. ⟨10.1097/MCO.0000000000000382⟩
Journal articles hal-03791386v1
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A method for the unbiased and efficient segmental labelling of RNA-binding proteins for structure and biophysics

Christopher Gallagher , Fabienne Burlina , John Offer , Andres Ramos
Scientific Reports, 2017, 7, pp.14083. ⟨10.1038/s41598-017-13950-8⟩
Journal articles hal-01634008v1
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Deep conservation of bivalve nacre proteins highlighted by shell matrix proteomics of the Unionoida Elliptio complanata and Villosa lienosa.

Benjamin Marie , Jaison Arivalagan , Lucrèce Mathéron , Gérard Bolbach , Sophie Berland , et al.
Journal of the Royal Society Interface, 2017, 14 (126), pp.20160846. ⟨10.1098/rsif.2016.0846⟩
Journal articles hal-01470764v1
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Membrane re-arrangements and rippled phase stabilisation by the cell penetrating peptide penetratin

Claudia Almeida , Antonin Lamazière , Angélique Filleau , Yohann Corvis , Philippe Espeau , et al.
Biochimica et Biophysica Acta:Biomembranes, 2016, 1858 (11), pp.2584-2591. ⟨10.1016/j.bbamem.2016.07.012⟩
Journal articles hal-01376840v1

Gender-Specific Toxicological Effects of Chronic Exposure to Pure Microcystin-LR or Complex Microcystis aeruginosa Extracts on Adult Medaka Fish

Séverine Le Manach , Nour Khenfech , Hélène Huet , Qin Qiao , Charlotte Duval , et al.
Environmental Science and Technology, 2016, 50 (15), pp.8324 - 8334. ⟨10.1021/acs.est.6b01903⟩
Journal articles hal-01493981v1

A backbone amide protecting group for overcoming difficult sequences and suppressing aspartimide formation.

Abu-Baker M Abdel-Aal , George Papageorgiou , Richard Raz , Martin Quibell , Fabienne Burlina , et al.
Journal of Peptide Science, 2016, 22 (5), pp.360-367. ⟨10.1002/psc.2877⟩
Journal articles hal-01304373v1

ECL1i, d(LGTFLKC), a novel, small peptide that specifically inhibits CCL2-dependent migration

C. Auvynet , C. Baudesson de Chanville , P. Hermand , K. Dorgham , C. Piesse , et al.
FASEB Journal, 2016, 30 (6), pp.2370-2381. ⟨10.1096/fj.201500116⟩
Journal articles hal-01306598v1
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Proteomic comparison of the EWS-FLI1 expressing cells EF with NIH-3T3 and actin remodeling effect of (R/W)9 cell-penetrating peptide

Séverine Clavier , Françoise Illien , Sandrine Sagan , Gérard Bolbach , Emmanuelle Sachon
EuPA Open Proteomics, 2016, 10, pp.1-8. ⟨10.1016/j.euprot.2015.10.002⟩
Journal articles hal-01365335v1

Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy

Monica Rolando , Pedro Escoll , Tamara Nora , Joëlle Botti , Valérie Boitez , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (7), pp.1901 - 1906. ⟨10.1073/pnas.1522067113⟩
Journal articles hal-01376135v1
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Quantitative fluorescence spectroscopy and flow cytometry analyses of cell-penetrating peptides internalization pathways: optimization, pitfalls, comparison with mass spectrometry quantification

Françoise Illien , Nicolas Rodriguez , Mehdi Amoura , Alain Joliot , Manjula Pallerla , et al.
Scientific Reports, 2016, 6, pp.36938 - 36938. ⟨10.1038/srep36938⟩
Journal articles hal-01397297v1
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5′ to 3′ Unfolding Directionality of DNA Secondary Structures by Replication Protein A

Layal Safa , Nassima Meriem Gueddouda , Frédéric Thiébaut , Emmanuelle Delagoutte , Irina Petruseva , et al.
Journal of Biological Chemistry, 2016, 291 (40), pp.21246-21256. ⟨10.1074/jbc.M115.709667⟩
Journal articles hal-01404053v1
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Deep sexual dimorphism in adult medaka fish liver highlighted by multi-omic approach

Qin Qiao , Séverine Le Manach , Benoit Sotton , Hélène Huet , Evelyne Duvernois-Berthet , et al.
Scientific Reports, 2016, 6, pp.32459. ⟨10.1038/srep32459⟩
Journal articles hal-01368277v1
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Laser induced post-desolvation of MALDI clusters

Laurent Diologent , Gérard Bolbach , Cristian Focsa , Michael Ziskind , Isabelle Fournier
International Journal of Mass Spectrometry, 2016, 416, pp.29-36. ⟨10.1016/j.ijms.2016.12.005⟩
Journal articles hal-01420190v1

An integrated omic analysis of hepatic alteration in medaka fish chronically exposed to cyanotoxins with possible mechanisms of reproductive toxicity

Qin Qiao , Séverine Le Manach , Hélène Huet , Evelyne Duvernois-Berthet , Soraya Chaouch , et al.
Environmental Pollution, 2016, 219, pp.119 - 131. ⟨10.1016/j.envpol.2016.10.029⟩
Journal articles hal-01493865v1
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Snapshot of sequential SNARE assembling states between membranes shows that N-terminal transient assembly initializes fusion

Yong Jian Wang , Feng Li , Nicolas Rodriguez , Xavier Lafosse , Christine Gourier , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (13), pp.3533-3538. ⟨10.1073/pnas.1518935113⟩
Journal articles hal-01297850v1

Structure-Guided Optimization of DNA Methyltransferase Inhibitors

Alexandre Erdmann , Paola B. Arimondo , Dominique Guianvarc'H
Book sections hal-01365334v1
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Peptide Synthesis Hot Paper HF-Free Boc Synthesis of Peptide Thioesters for Ligation and Cyclization

Richard Raz , Fabienne Burlina , Mohamed Ismail , Julian Downward , Jiejin Li , et al.
Angewandte Chemie, 2016, 128 (42), pp.13368-13373 ⟨10.1002/ange.201607657⟩
Journal articles hal-01371556v1
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How to unveil self-quenched fluorophores and subsequently map the subcellular distribution of exogenous peptides

Jean-Marie Swiecicki , Frédéric Thiebaut , Margherita Di Pisa , Simon Gourdin-Bertin , Julien Tailhades , et al.
Scientific Reports, 2016, 6, pp.20237. ⟨10.1038/srep20237⟩
Journal articles hal-01279453v1

The sequence Pro(295)-Thr(311) of the hinge region of oestrogen receptor alpha is involved in ERK1/2 activation via GPR30 in leiomyoma cells

Denis Leiber , Fabienne Burlina , Cillian Byrne , Philippe Robin , Christophe Piesse , et al.
Biochemical Journal, 2015, 472 (1), pp.97-109. ⟨10.1042/BJ20150744⟩
Journal articles hal-01362855v1

cis-Acting RNA elements in the hepatitis C virus RNA genome.

Selena Sagan , Jasmin Chahal , Peter Sarnow
Virus Research, 2015, 206, pp.90-98. ⟨10.1016/j.virusres.2014.12.029⟩
Journal articles hal-01302119v1

Accumulation of Cell-Penetrating Peptides in Large Unilamellar Vesicles - A straightforward Screening Assay for Investigating the Internalization Mechanism.

Jean-Marie Swiecicki , Margherita Di Pisa , Fabienne Burlina , Pascaline Lécorché , Christelle Mansuy , et al.
Biopolymers, 2015, 104 (5), pp.533-543 ⟨10.1002/bip.22652⟩
Journal articles istex hal-01140970v1
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Photocross-Linked Peptide-Protein Complexes Analysis: A Comparative Study of CID and ETD Fragmentation Modes

Séverine Clavier , Gérard Bolbach , Emmanuelle Sachon
Journal of The American Society for Mass Spectrometry, 2015, 26 (6), pp.1014-1026. ⟨10.1007/s13361-015-1095-0⟩
Journal articles hal-01140193v1

Evidence for annexin A6-dependent plasma membrane remodelling of lipid domains

Anna Alvarez-Guaita , Sandra Vila De Muga , Dylan M. Owen , David Williamson , Astrid Magenau , et al.
British Journal of Pharmacology, 2015, 172 (7, Special issue ANNEXINS VII PROGRAMME), pp.1677-1690. ⟨10.1111/bph.13022⟩
Journal articles hal-01365339v1
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Massive glycosaminoglycan-dependent entry of Trp-containing cell-penetrating peptides induced by exogenous sphingomyelinase or cholesterol depletion.

Chérine Bechara , Manjula Pallerla , Fabienne Burlina , Françoise Illien , Sophie Cribier , et al.
Cellular and Molecular Life Sciences, 2015, 72 (4), pp.809-820. ⟨10.1007/s00018-014-1696-y⟩
Journal articles hal-01056015v1

Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.

Serena Sanulli , Neil Justin , Aurélie Teissandier , Katia Ancelin , Manuela Portoso , et al.
Molecular Cell, 2015, 57 (5), pp.769-783. ⟨10.1016/j.molcel.2014.12.020⟩
Journal articles hal-01110498v1

Pachymodulin, a new functional formyl peptide receptor 2 (FPR2) peptidic ligand isolated from frog skin, has Janus-like immunomodulatory capacities.

Claire Lacombe , Christophe Piesse , Sandrine Sagan , Christophe Combadiere , Yvonne Rosenstein , et al.
Korean Journal of Medicinal Chemistry, 2015, 58 (3), pp.1089-1099. ⟨10.1021/jm501018q⟩
Journal articles hal-01103863v1