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Structural analysis of unstable norbixin isomers guided by pure shift nuclear magnetic resonance

Gildas Bertho , Imed Eddine Oumezziane , Cédric Caradeuc , Louis Guibout , Christine Balducci , et al.
Magnetic Resonance in Chemistry, 2022, 60 (5), pp.504-514. ⟨10.1002/mrc.5252⟩
Journal articles hal-03648920v1

Antifungal activity of [K 3 ]temporin-SHa against medically relevant yeasts and moulds

Kévin Brunet , Julien Verdon , Ali Ladram , Simon Arnault , Marie-Hélène Rodier , et al.
Canadian Journal of Microbiology, 2022, pp.1-8. ⟨10.1139/cjm-2021-0250⟩
Journal articles hal-03626630v1
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Recent Advances in Multifunctional Antimicrobial Peptides as Immunomodulatory and Anticancer Therapy: Chromogranin A-Derived Peptides and Dermaseptins as Endogenous versus Exogenous Actors

Francesco Scavello , Mohamed Amiche , Jean-Eric Ghia
Pharmaceutics, 2022, 14 (10), pp.2014. ⟨10.3390/pharmaceutics14102014⟩
Journal articles hal-03784206v1
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Testing the efficacy and safety of BIO101, for the prevention of respiratory deterioration, in patients with COVID-19 pneumonia (COVA study): a structured summary of a study protocol for a randomised controlled trial

W. Dioh , M. Chabane , C. Tourette , A. Azbekyan , C. Morelot-Panzini , et al.
Trials, 2021, 22 (1), pp.42. ⟨10.1186/s13063-020-04998-5⟩
Journal articles hal-03113218v1
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20-Hydroxyecdysone, from Plant Extracts to Clinical Use: Therapeutic Potential for the Treatment of Neuromuscular, Cardio-Metabolic and Respiratory Diseases

Laurence Dinan , Waly Dioh , Stanislas Veillet , Rene Lafont
Biomedicines, 2021, 9 (5), pp.492. ⟨10.3390/biomedicines9050492⟩
Journal articles hal-03219775v1
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Antitumor Activity and Mechanism of Action of Hormonotoxin, an LHRH Analog Conjugated to Dermaseptin-B2, a Multifunctional Antimicrobial Peptide

Mickael Couty , Marie Dusaud , Micka Miro-Padovani , Liuhui Zhan , Patricia Zadigue , et al.
International Journal of Molecular Sciences, 2021, 22 (21), pp.11303. ⟨10.3390/ijms222111303⟩
Journal articles hal-03388092v1
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High Performance Thin-Layer Chromatography of Plant Ecdysteroids Coupled with Desorption Electrospray Ionisation-Ion Mobility-Time of Flight High Resolution Mass Spectrometry (HPTLC/DESI/IM/ToFMS)

E. Claude , M. Tower , R. Lafont , I.D. Wilson , R.S. Plumb
Chromatographia, 2020, ⟨10.1007/s10337-020-03917-9⟩
Journal articles hal-02878364v1

Antileishmanial Drugs Modulate IL-12 Expression and Inflammasome Activation in Primary Human Cells

Sonia André , Vasco Rodrigues , Sarah Pemberton , Mireille Laforge , Yasmina Fortier , et al.
Journal of Immunology, 2020, 204 (7), pp.1869-1880. ⟨10.4049/jimmunol.1900590⟩
Journal articles hal-03089820v1
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In vitro and intracellular activities of frog skin temporins against Legionella pneumophila and its eukaryotic hosts

Alexandre Crépin , Jean-Francois Jégou , Sonia André , Florine Ecale , Anastasia Croitoru , et al.
Scientific Reports, 2020, 10 (1), pp.3978. ⟨10.1038/s41598-020-60829-2⟩
Journal articles inserm-02505077v1
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Beyond AREDS Formulations, What Is Next for Intermediate Age-Related Macular Degeneration (iAMD) Treatment? Potential Benefits of Antioxidant and Anti-inflammatory Apocarotenoids as Neuroprotectors

Serge Camelo , Mathilde Latil , Stanislas Veillet , Pierre Dilda , René Lafont
Oxidative Medicine and Cellular Longevity, 2020, 2020, pp.4984927. ⟨10.1155/2020/4984927⟩
Journal articles hal-03128846v1
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Functional Characterization of Temporin-SHe, a New Broad-Spectrum Antibacterial and Leishmanicidal Temporin-SH Paralog from the Sahara Frog (Pelophylax saharicus)

Sonia André , Zahid Raja , Vincent Humblot , Christophe Piesse , Thierry Foulon , et al.
International Journal of Molecular Sciences, 2020, 21 (18), pp.6713. ⟨10.3390/ijms21186713⟩
Journal articles hal-02989769v1
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Ribozyme Chemistry: to be or not to be under high pressure

Marie Christine Maurel , Fabrice Leclerc , Guy Hervé
Chemical Reviews, 2019, 120 (11), pp.4898-4918. ⟨10.1021/acs.chemrev.9b00457⟩
Journal articles hal-02317015v2
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The effects of curcumin, mangiferin, resveratrol and other natural plant products on aminopeptidase B activity

Sandrine Cadel , Cécile Darmon , Alexandre Désert , Mouna Mahbouli , Christophe Piesse , et al.
Biochemical and Biophysical Research Communications, 2019, 512 (4), pp.832-837. ⟨10.1016/j.bbrc.2019.02.143⟩
Journal articles hal-02189376v1

Pressure-induced activation of latent Dihydroorotase from Aquifex aeolicus as revealed by high pressure protein crystallography

Thierry Prangé , Eric Girard , Roger Fourme , Anne-Claire Dhaussy , Brian Edwards , et al.
FEBS Journal, 2019, 286 (6), pp.1204-1213. ⟨10.1111/febs.14758⟩
Journal articles hal-01989014v1
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Comparison of Anti-Viral Activity of Frog Skin Anti-Microbial Peptides Temporin-Sha and [K3]SHa to LL-37 and Temporin-Tb against Herpes Simplex Virus Type 1

Maëva Roy , Lucie Lebeau , Céline Chessa , Alexia Damour , Ali Ladram , et al.
Viruses, 2019, 11 (1), pp.77. ⟨10.3390/v11010077⟩
Journal articles hal-02066789v1

In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design

William Porto , Luz Lu , Eliane Alves , Suzana Ribeiro , Carolina Matos , et al.
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-03746-3⟩
Journal articles hal-01767730v1
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Size matters! Aurora A controls Drosophila larval development

Lucie Vaufrey , Christine Balducci , René Lafont , Claude Prigent , Stéphanie Le Bras
Developmental Biology, 2018, 440 (2), pp.88-98. ⟨10.1016/j.ydbio.2018.05.005⟩
Journal articles hal-01812516v1
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Functional Characterization and Signaling Systems of Corazonin and Red Pigment Concentrating Hormone in the Green Shore Crab, Carcinus maenas

Jodi L Alexander , Andrew Oliphant , David C Wilcockson , Neil Audsley , Rachel E Down , et al.
Frontiers in Neuroscience, 2018, 11, pp.752. ⟨10.3389/fnins.2017.00752⟩
Journal articles hal-01696475v1

Structural Insight into the Core of CAD

Guy Hervé
Structure, 2017, 25 (6), pp.819-820. ⟨10.1016/j.str.2017.05.014⟩
Journal articles hal-01558868v1
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Insight into the mechanism of action of temporin-SHa, a new broad-spectrum antiparasitic and antibacterial agent

Zahid Raja , Sonia André , Feten Abbassi , Vincent Humblot , Olivier Lequin , et al.
PLoS ONE, 2017, 12 (3), pp.e0174024. ⟨10.1371/journal.pone.0174024⟩
Journal articles hal-01517346v1

Activation of Latent Dihydroorotase from Aquifex aeolicus by Pressure

Guy Hervé , Hedeel Guy Evans , Roshini Fernado , Chandni Patel , Fatme Hachem , et al.
Journal of Biological Chemistry, 2017, 292 (2), pp.629-637. ⟨10.1074/jbc.M116.739862⟩
Journal articles hal-01558866v1
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Serine Protease Inhibitors in Ticks: An Overview of Their Role in Tick Biology and Tick-Borne Pathogen Transmission

Adrien A. Blisnick , Thierry Foulon , Sarah I. Bonnet
Frontiers in Cellular and Infection Microbiology, 2017, 7, pp.199. ⟨10.3389/fcimb.2017.00199⟩
Journal articles hal-01536659v1

Ecdysteroid Chemistry and Biochemistry

René Lafont , C. Dauphin-Villemant , J.T. Warren , H.H. Rees
Reference Module in Life Sciences, Elsevier, 2017, 978-0-12-809633-8. ⟨10.1016/B978-0-12-809633-8.04026-7⟩
Book sections hal-01558867v1

Selective amino acid substitution reduces cytotoxicity of the antimicrobial peptide mastoparan

Luz N. Irazazabal , William F. Porto , Suzana M. Ribeiro , Sandra Casale , Vincent Humblot , et al.
Biochimica et Biophysica Acta:Biomembranes, 2016, 1858 (11), pp.2699-2708. ⟨10.1016/j.bbamem.2016.07.001⟩
Journal articles hal-01558870v1

Proteomic and functional analysis of proline dehydrogenase 1 link proline catabolism to mitochondrial electron transport in Arabidopsis thaliana

Cecile Cabassa-Hourton , Peter Schertl , Marianne Bordenave-Jacquemin , Kaouthar Saadallah , Anne Guivarc'H , et al.
Biochemical Journal, 2016, 473 (17), pp.2623-2634. ⟨10.1042/BCJ20160314⟩
Journal articles hal-01558869v1
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Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo

Valérie Fontaine , Elodie Monteiro , Elena Brazhnikova , Laëtitia Lesage , Christine Balducci , et al.
PLoS ONE, 2016, 11 (12), pp.e0167793. ⟨10.1371/journal.pone.0167793⟩
Journal articles hal-01484263v1

20-Hydroxyecdysone protects wheat seedlings (Triticum aestivum L.) against lead stress

Mostafa Lamhamdi , René Lafont , Kacem Rharrabe , Fouad Sayah , Ahmed Aarab , et al.
Plant Physiology and Biochemistry, 2016, 98, pp.64-71. ⟨10.1016/j.plaphy.2015.11.006⟩
Journal articles hal-01558871v1

The ecdysteroidome of Drosophila: influence of diet and development

Oksana Lavrynenko , Jonathan Rodenfels , Maria Carvalho , Natalie A. Dye , René Lafont , et al.
Development (Cambridge, England), 2015, 142 (21), pp.3758-3768. ⟨10.1242/dev.124982⟩
Journal articles hal-01558873v1

Structure-Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity

Sonia Andre , Shannon K. Washington , Emily Darby , Marvin M. Vega , Ari D. Filip , et al.
ACS Chemical Biology, 2015, 10 (10), pp.2257-2266. ⟨10.1021/acschembio.5b00495⟩
Journal articles hal-01537169v1
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The M1 family of vertebrate aminopeptidases: Role of evolutionarily conserved tyrosines in the enzymatic mechanism of aminopeptidase B

Sandrine Cadel , Cecile Darmon , Julien Pernier , Guy Hervé , Thierry Foulon
Biochimie, 2015, 109, pp.67-77. ⟨10.1016/j.biochi.2014.12.009⟩
Journal articles hal-01558872v1